Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Tsugane, S.
Right arrow Articles by Suemasu, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tsugane, S.
Right arrow Articles by Suemasu, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Japanese Journal of Clinical Oncology 17:309-317 (1987)
© 1987 Foundation for Promotion of Cancer Research

research-article

Smoking, Occupation and Family History in Lung Cancer Patients under Fifty Years of Age

Shoichiro Tsugane, M.D.*,1, Shaw Watanabe, M.D.1, Haruhiko Sugimura, M.D.1, Hiroko Arimoto2, Yukio Shimosato, M.D.3 and Keiichi Suemasu, M.D.4

1Epidemiology, National Cancer Center Research Institute 1–1, Tsukiji 5-chome, Chuo-ku, Tokyo 104, Japan
2Radiology, National Cancer Center Research Institute 1–1, Tsukiji 5-chome, Chuo-ku, Tokyo 104, Japan
3Pathology Divisions, National Cancer Center Research Institute 1–1, Tsukiji 5-chome, Chuo-ku, Tokyo 104, Japan
4National Cancer Center Hospital Tokyo 104, Japan

*For reprints and all correspondence

Received July 17, 1987; accepted November 21, 1987

A hospital based case-control study was conducted to investigate the factors affecting the development of lung cancer among young adults. A total of 185 Inpatients (males: 128, females: 57) aged from 30 to 49 have been histologlcally classified in the National Cancer Center Hospital during the last 10 years. Most frequent was adenocarcinoma in both males (57.0%) and females (73.7%). Basic factors were obtained from clinical charts including smoking history, occupation and family history of cancers. Elevated risks were found for squamous cell carcinoma in patients with a history of smoking (all had smoked v. 15/20 for controls) and an occupation possibly related to respiratory irritations (15/20 v. 3/20 for controls). Heavy smokers were distributed more in the cancer patients. Moreover, the average Smoking Index among those without "at risk" occupation was 1, 002 with the least being 700, while that with such an occupation was 723. Heavy smoking alone and a smoking/occupation combination could contribute to an early onset of squamous cell carcinoma. On the other hand, there were no significant risk factors for adenocarcinoma, the relative risk from a history of smoking being less than 1.00 and from a family history of cancer, approximately 1.00.

Key Words: Lung cancer • Adenocarcinoma • Squamous cell carcinoma • Younger onset • Risk factors


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 ChestHome page
J.-i. Nitadori, M. Inoue, M. Iwasaki, T. Otani, S. Sasazuki, K. Nagai, S. Tsugane, and the JPHC Study Group
Association Between Lung Cancer Incidence and Family History of Lung Cancer: Data From a Large-Scale Population-Based Cohort Study, the JPHC Study.
Chest, October 1, 2006; 130(4): 968 - 975.
[Abstract] [Full Text] [PDF]

Home page
 Jpn J Clin OncolHome page
K. Wakai, M. Inoue, T. Mizoue, K. Tanaka, I. Tsuji, C. Nagata, S. Tsugane, and for the Research Group for the Development and Eva
Tobacco Smoking and Lung Cancer Risk: An Evaluation Based on a Systematic Review of Epidemiological Evidence Among the Japanese Population
Jpn. J. Clin. Oncol., May 1, 2006; 36(5): 309 - 324.
[Abstract] [Full Text] [PDF]

Home page
 Jpn J Clin OncolHome page
T. Marugame, I. Yoshimi, K.-i. Kamo, Y. Imamura, S. Kaneko, S. Mizuno, and T. Sobue
Trends in Lung Cancer Mortality Among Young Adults in Japan
Jpn. J. Clin. Oncol., April 1, 2005; 35(4): 177 - 180.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. A. Khuder and A. B. Mutgi
Effect of Smoking Cessation on Major Histologic Types of Lung Cancer
Chest, November 1, 2001; 120(5): 1577 - 1583.
[Abstract] [Full Text] [PDF]

Home page
 Indoor and Built EnvironmentHome page
P.N. Lee
Review : Epidemiological Studies Relating Family History of Lung Cancer to Risk of the Disease
Indoor and Built Environment, May 1, 1993; 2(3): 129 - 142.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.