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Japanese Journal of Clinical Oncology 19:283-286 (1989)
© 1989 Foundation for Promotion of Cancer Research


case-report

Pheochromocytoma Associated with Behçet's Disease

Seiichi Oishi, Bunji Koga, Masato Sasaki, Teruhisa Umeda and Tatsuo Sato*

Third Department of Internal Medicine, Kumamoto University School of Medicine Honjo 1-1-1, Kumamoto 860

*For reprints and all correspondence

Received September 30, 1988; accepted February 27, 1989

A 32-yr-old man was admitted to our clinic complaining chiefly of paroxysmal attacks of headaches and palpitations. He had had intermittent episodes of joint pains, erythema nodosum-like eruptions of the lower limbs, oral aphtha, and a fever lasting for three years. Ultrasonography, computerized tomography and magnetic resonance imaging scanning showed a mass in the left adrenal gland. A diagnosis of pheochromocytoma was made from the elevated plasma and urinary catecholamines and abnormal uptake of 131I-metaiodobenzylguanidine The tumor was successfully removed, and the patient's plasma and urinary catecholamine levels returned to within the normal range. High fever, aphtha of the mouth, erythema of the lower extremities and genital ulcers were, however, frequently observed. A diagnosis of Behçet's disease was then established. The association of the pheochromocytoma with Behçet's disease was thought to be a chance one: to our knowlege, this has been the first case of a pheochromocytoma associated with Behçet's disease.

Key Words: Pheochromocytoma • Behçet's disease • Adrenal gland


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Arch Intern MedHome page
D. L. Gordon, S. D. Atamian, M. H. Brooks, P. Gattuso, M. J. Castelli, J. Valaitis, and W. Thomas Jr
Fever in Pheochromocytoma
Arch Intern Med, June 1, 1992; 152(6): 1269 - 1272.
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