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Japanese Journal of Clinical Oncology, Vol 28, Issue 1 27-29, Copyright © 1998 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

Cerebral metastasis in patients with uterine cervical cancer

S Ikeda, T Yamada, N Katsumata, K Hida, K Tanemura, R Tsunematu, K Ohmi, T Sonoda, H Ikeda and K Nomura
Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan.

We report on eight patients who developed brain metastases following uterine cervical cancer. The mean interval between diagnosis of the primary cancer and diagnosis of the brain metastasis was 28.4 months (range: 6.1-61.8 months). Nausea and vomiting due to increased intracranial pressure were the most frequent symptoms. Surgical excision of the brain lesions, followed by postoperative radiotherapy, was performed in three patients. The other five patients received only cranial radiotherapy. When the metastatic brain lesions were detected, other distant metastatic lesions were confirmed at the same time in five patients. The median survival time after diagnosis of the brain metastases was only 3.0 months.
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