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Japanese Journal of Clinical Oncology, Vol 29, Issue 11 582-586, Copyright © 1999 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

Cisplatin-5-fluorouracil therapy with remarkable effect and 5-year survival for paraaortic lymph node metastases of rectal carcinoma in females: a case report

T Takenoue, Y Yamada, S Miyagawa, Y Akiyama, K Koyama and H Nagawa
Department of Surgical Oncology, The University of Tokyo, Japan. takenoue-1su@h.u-tokyo.ac.jp

A 68-year-old woman was admitted because of a rectal carcinoma with huge paraaortic lymph node metastases. Low anterior resection with regional lymph node dissection was performed, leaving the paraaortic mass. After the operation, cisplatin-5-fluorouracil therapy was used as supplemental chemotherapy. The metastatic lymph nodes shrank remarkably in response to anticancer drugs. We evaluated the effect of chemotherapy as a partial response. The physical condition of the patient was well controlled for more than 4 years until she was admitted again because of cardiac failure accompanied by relapse of abdominal lymph node swelling. She died of cardiac failure 5 years and 3 days after the operation.
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