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Japanese Journal of Clinical Oncology, Vol 29, Issue 2 106-108, Copyright © 1999 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

A case of advanced esophageal cancer showing a long-term complete response with chemotherapy with nedaplatin alone

T Satoh, K Tsushima, S Saitoh, Y Hizawa, Y Tamura, S Fukuda, Y Yamada, H Tohno, T Takasugi, Y Sakata and A Munakata
First Department of Internal Medicine, Hirosaki University School of Medicine, Aomori, Japan. tsatoh-hki@umin.u-tokyo.ac.jp

We describe a case of advanced esophageal cancer treated successfully by chemotherapy with nedaplatin alone. A 60-year-old male with type 2 advanced esophageal cancer, which was located in the upper part of the esophagus and had invaded adjacent organs, was treated with nedaplatin 150 mg/body (100 mg/m2) given intravenously every 4 weeks from January 6, 1991. He achieved a partial response (PR) and was discharged in March 1991. Subsequently, he received nedaplatin 75 mg/body in an out-patient setting almost every month until August 1992. Toxicities were tolerable and included mild thrombocytopenia and nausea/vomiting. From serial evaluation in October 1993, the esophageal tumor was not observed. After 7 years since initial chemotherapy was administered, he still survives without the disease.
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