Japanese Journal of Clinical Oncology, Vol 29, Issue 4 198-203, Copyright © 1999 by Foundation for Promotion of Cancer Research
H Fujimoto, F Wakao, N Moriyama, K Tobisu, M Sakamoto and T Kakizoe
BACKGROUND: To establish the correlation between tumor appearance on CT and
tumor histology in renal cell carcinomas. METHODS: The density and
attenuation patterns of 96 renal cell carcinomas, each < or = 5 cm in
greatest diameter, were studied by non-enhanced CT and early and late after
bolus injection of contrast medium using dynamic CT. The density and
attenuation patterns and pathological maps of each tumor were individually
correlated. RESULTS: High attenuated areas were present in 72 of the 96
tumors on early enhanced dynamic CT scanning. All 72 high attenuated areas
were of the clear cell renal cell carcinoma and had alveolar architecture.
The remaining 24 tumors that did not demonstrate high attenuated foci on
early enhanced scanning included three clear cell, nine granular cell, six
papillary, five chromophobe and one collecting duct type. With respect to
tumor architecture, all clear cell tumors of alveolar architecture
demonstrated high attenuation on early enhanced scanning. CONCLUSION: Clear
cell renal cell carcinomas of alveolar architecture show high attenuation
on early enhanced dynamic CT scanning. A larger number of patients are
indispensable to obtaining clear results. However, these findings seem to
be an important clue to the diagnosis of renal cell carcinomas as having an
alveolar structure.
CASE REPORTS
Alveolar architecture of clear cell renal carcinomas (< or = 5.0 cm) show high attenuation on dynamic CT scanning
Department of Urology, National Cancer Center Hospital, Tokyo, Japan.
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