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Japanese Journal of Clinical Oncology, Vol 29, Issue 8 390-394, Copyright © 1999 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

Multiple liver metastases of breast cancer: report of a case successfully treated with hormone-cytokine-chemotherapy

Y Naomoto, H Sadamori, H Matsukawa, Y Shirakawa, T Yamatsuji, S Saito, N Hino, H Isozaki, N Takakura and N Tanaka
First Department of Surgery, Okayama University Medical School, Japan.

The prognosis of patients with hepatic metastasis from breast cancer is usually extremely poor. We present the case of a 39-year-old Japanese woman diagnosed with multiple liver metastasis from breast cancer. A novel approach consisting of hormone-cytokine-chemotherapy with an arterial infusion therapy was carried out. Computed tomography and ultrasonography revealed that the multiple liver metastases were reduced with remaining calcification. Tumor markers decreased rapidly. Complete regression was achieved after these treatments. To date, there has been no relapse during the 8-year follow-up period. These results suggest that the hormone-cytokine-chemotherapy might be a rational modality of treatment against multiple metastatic breast cancer.
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