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Japanese Journal of Clinical Oncology 30:37-39 (2000)
© 2000 Foundation for Promotion of Cancer Research

Pulmonary Lymphangitic Sarcomatosis from Cutaneous Angiosarcoma: an Unusual Presentation of Diffuse Interstitial Lung Disease

Chi-Ting Liau1, Shih-Ming Jung2, Kun-Eng Lim3 and Hsin-Nung Shih4,+

1Division of Hematology–Oncology, Department of Internal Medicine, 2Department of Pathology, 3Department of Diagnostic Radiology and 4Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan

Pulmonary lymphangitic sarcomatosis (PLS) is not much recognized clinically although it shows similar pathological patterns and diagnostic features to pulmonary lymphangitic carcinomatosis (PLC). We report a case with hand angiosarcoma whose chest X-ray findings revealed a diffuse interstitial pattern consistent with lymphangitic spreading. The final diagnosis was made by open lung biopsy. The clinical, diagnostic and pathological features of this disease process are reviewed.

+ For reprints and all correspondence: Chi-Ting Liau, Division of Hematology–Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, 199 Tung Hwa North Road, Taipei, Taiwan. E-mail: gerson@ms2.hinet.netAbbreviations: PLC, pulmonary lymphangitic carcinomatosis; PLS, pulmonary lymphangitic sarcomatosis; IVBATs, intravascular bronchioalveolar tumors; MRI, magnetic resonance imaging; CT, computerized tomography; FEV1, forced expiratory volume at 1 s; FVC, forced vital capacity; DLco, diffusing capacity of the lungs for carbon monoxide; BAL, bronchoalveolar lavage


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