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Japanese Journal of Clinical Oncology 30:241-245 (2000)
© 2000 Foundation for Promotion of Cancer Research

Local Recurrence of Renal Cell Carcinoma Causing Massive Gastrointestinal Bleeding: A Report of Two Patients Who Underwent Surgical Resection

Yasushi Ohmura, Tetsuya Ohta, Hiroyoshi Doihara and Nobuyoshi Shimizu+

Department of Surgery II, Okayama University School of Medicine, Okayama, Japan

We report two cases of local recurrence of renal cell carcinoma, which invaded the gastrointestinal tract. The intervals to local recurrence after primary nephrectomies were 5 and 13 years. Both cases developed massive gastrointestinal bleeding. Blood transfusions and arterial embolization were performed; however, continuous melena prevented improvement in their general condition. Although distant metastases were observed in both cases, tumor resections combined with intestine invasion were performed. Although this surgical approach does not significantly improve the prognosis, even in patients who have remaining metastatic lesions, it may provide palliation and improve the quality of survival.

+ For reprints and all correspondence: Yasushi Ohmura, Department of Surgery II, Okayama University School of Medicine, 2–5–1, Shikata, Okayama 700-8558, JapanAbbreviations: RCC, renal cell carcinoma; PS, performance status; WHO, World Health Organization; Ki-67 L.I., Ki-67 labeling index; PCNA, proliferating cell nuclear antigen; AgNOR, silver-stained nucleolar organizer regions


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