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Japanese Journal of Clinical Oncology 31:35-38 (2001)
© 2001 Foundation for Promotion of Cancer Research

A 7 mm Lung Adenocarcinoma with Mediastinal Involvement and Lymphangiosis Carcinomatosa: A Case Report

Hidenori Kawasaki1, Kanji Nagai1, Tomoyuki Yokose2, Junji Yoshida1, Hironobu Ohmatsu1 and Yutaka Nishiwaki1,+

1Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba and 2Pathology Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan

We report a case of a 46-year-old man with a 7 mm lung adenocarcinoma with mediastinal nodal involvement and lymphangiosis carcinomatosa. The resected right middle lobe contained a 7 mm well-differentiated papillary adenocarcinoma and lymphatic vessels towards the hilum were severely involved. The disease was pathologically diagnosed as T1N2M0. Six months after the operation, malignant pleural effusion and multiple bone metastases developed and he died 21 months after the operation. This case indicates that even a very small-sized lung cancer, 1 cm or smaller, could be biologically highly malignant.

+ For reprints and all correspondence: Hidenori Kawasaki, Division of Thoracic Surgery, National Okinawa Hospital, 3–20–14, Ganeko, Ginowann, Okinawa 901-2214, Japan. E-mail: hkawasak@sub-tky.hosp. go.jp


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