Japanese Journal of Clinical Oncology 31:536-540 (2001)
© 2001 Foundation for Promotion of Cancer Research
Treated Natural History of Superficial Bladder Cancer
1Department of Urology, Nara Medical University, Kashihara, 2Faculty of Medicine, Pharmacoepidemiology, The University of Tokyo, Tokyo, 3School of Health Sciences and Nursing, Biostatistics, The University of Tokyo, Tokyo, 4Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba and 5Department of Pathology, School of Medicine, Osaka Municipal University, Osaka, Japan
Background: The present study was conducted to examine the natural history of superficial bladder cancer.
Methods: One hundred and forty-four patients with superficial bladder cancer who had been treated with transurethral resection of bladder tumor (TURBt) alone were analyzed.
Results: The non-recurrence rate was 64.8% at 36 months and 61.2% at 60 months after TURBt. When the non-recurrence rate after TURBt was analyzed by background variables, the rate differed significantly between the solitary tumor group and the multiple tumor group. The tumor recurrence hazard curves for the entire population had one high peak before 500 days and another slight peak around 1500 days after TURBt.
Conclusions: These results will provide basic information useful when evaluating new regimens of intravesical instillation therapy for prophylaxis of superficial bladder cancer after our complete TURBt in the Nara Uro-Oncology Research Group.
+ For reprints and all correspondence: Seiichiro Ozono, Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan. E-mail: ozn-kkr@nmu-gw.naramed-u.ac.jp