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Japanese Journal of Clinical Oncology 31:119-121 (2001)
© 2001 Foundation for Promotion of Cancer Research

Hepatocellular Carcinoma with Pancoast’s Syndrome as an Initial Symptom: a Case Report

Chao-Fu Chang1, Wei-Juin Su2, Teh-Ying Chou3 and Reury-Perng Perng2,+

1Department of Internal Medicine, 2Division of Pulmonary Immunology and Infectious Diseases, Chest Department and 3Department of Pathology, Taipei Veterans General Hospital, National Yang-Ming University School of Medicine, Taipei, Taiwan

Pancoast’s syndrome refers to a condition consisting of Horner’s syndrome and arm pain that is most commonly found in patients with a lung tumor of the superior sulcus invading the upper ribs or spine, lower brachial plexus and sympathetic chain. We report a 76-year-old female who had a thoracic inlet mass that presented as Pancoast’s syndrome, showing profound pain, numbness and weakness of the left upper limb. Further evaluation revealed an increased level of serum {alpha}-fetoprotein (24 278 ng/ml), cryptogenic liver cirrhosis and primary hepatocellular carcinoma with protruding T3 vertebra metastasis that resulted in Pancoast’s syndrome. To our knowledge, it is a rare case and only one case has been reported previously.

+ For reprints and all correspondence: Wei-Juin Su, Chest Department, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan. E-mail: wjsu@vghtpe.gov.tw


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