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Japanese Journal of Clinical Oncology 32:33-34 (2002)
© 2002 Foundation for Promotion of Cancer Research

Dose-intensive Chemotherapy with Syngeneic Peripheral Blood Stem Cell Support for Poor Risk Germ Cell Tumor of Extragonadal Origin: a Case Report

Takashi Kobayashi, Shingo Yamamoto, Eijiro Nakamura, Toshiyuki Kamato, Yoshiyuki Kakehi, Osamu Ogawa, Noriyuki Ito, Takuo Fukuyama, Masakatsu Hishizawa and Tatsuo Ichinohe,+,§

1Department of Urology, Kyoto University Hospital, 2Department of Urology, Kyoto National Hospital and 3Department of Hematology and Oncology, Kyoto University Hospital, Kyoto, Japan

A variety of regimens of high-dose chemotherapy with hematopoietic stem cell support for poor risk germ cell tumors have been established. However, a series of chemotherapy steps carried out prior to the harvest sometimes leads to an insufficient number of peripheral blood stem cells. Here, we report a case of a patient who successfully underwent high-dose chemotherapy for the treatment of poor risk extragonadal germ cell tumor by receiving peripheral blood stem cell transplantation donated from his genomically identical twin brother.

+ For reprints and all correspondence: Osamu Ogawa, Department of Urology, Kyoto University Hospital, Shogoin Kawahara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan. E-mail: ogawao@kuhp.kyoto-u.ac.jp

§ Abbreviations: TI, chemotherapy consisting of paclitaxel and ifosfamide; CE, chemotherapy consisting of carboplatin and etoposide, PBSCT, peripheral blood stem cell transplantation


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