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Japanese Journal of Clinical Oncology 34:46-49 (2004)
© 2004 Foundation for Promotion of Cancer Research

Late Pulmonary Metastasis of Renal Cell Carcinoma Resected 25 Years after Nephrectomy

Satoshi Shiono1, Junji Yoshida1, Mitsuyo Nishimura1, Junichi Nitadori1, Genichiro Ishii2, Yutaka Nishiwaki1 and Kanji Nagai1,+

1 Department of Thoracic Oncology, National Cancer Center Hospital East and 2 Pathology Division, National Cancer Center Research Institute East, Kashiwa, Chiba, Japan

A 50-year-old male underwent a left nephrectomy for clear cell type renal cell carcinoma (RCC) in February 1978. A right pulmonary metastasis was resected in February 1994. At that time, chest computed tomography revealed the presence of three small nodules in the left lung, but these were followed up as inflammatory lesions. In January 2002, a right pleural metastasis, which showed rapid growth, was detected and it was resected in June of the same year. A gradual growth was observed in the left lung nodules, and the patient underwent wedge resection of the left lung in March 2003, 25 years after nephrectomy. These nodules were diagnosed as metastatic RCC. Currently, the patient is doing well with no signs of recurrence, 8 months after the third metastasectomy.

+ For reprints and all correspondence: Junji Yoshida, Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba 277-8577, Japan. E-mail: jyoshida{at}east.ncc.go.jp


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