Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (12)
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Ali, R.
Right arrow Articles by Tunali, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ali, R.
Right arrow Articles by Tunali, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Japanese Journal of Clinical Oncology 34:215-217 (2004)
© 2004 Foundation for Promotion of Cancer Research

Successful Pregnancy and Delivery in a Patient with Chronic Myelogenous Leukemia (CML), and Management of CML with Leukapheresis during Pregnancy: a Case Report and Review of the Literature

Ridvan Ali1, Fahir Özkalemkas1, Vildan Özkocaman1, Tülay Özçelik1, Ülkü Ozan1, Yalçin Kimya2 and Ahmet Tunali1,+

1 Division of Hematology, Department of Internal Medicine and 2 Department of Obstetrics and Gynecology, Uludag University School of Medicine, Uludag University Hospital, Bursa, Turkey

Although infrequently seen, the management of cancer during pregnancy can be difficult for patients, their families and physicians. The concomitant occurrence of pregnancy and chronic myelogenous leukemia is uncommon. We describe the successful management of a 26-year-old woman in the first trimester of her pregnancy with chronic myelogenous leukemia (CML) in chronic phase by using only leukapheresis. She was treated with leukapheresis until her delivery at 36 weeks of gestation. The procedure was without significant adverse effects on the patient or fetus. We applied a total of 15 leukapheresis treatments throughout the pregnancy. The patient gave birth vaginally to a healthy 2800 g boy at 36 weeks of gestation. We conclude that leukapheresis may provide an alternative treatment to chemotherapy, {alpha}-interferon or imatinib in pregnant patients with CML, particularly with concern over their potential teratogenic and other adverse effects.

+ For reprints and all correspondence: Ridvan Ali, Division of Hematology, Department of Internal Medicine, Uludag University School of Medicine, Uludag University Hospital, 16059, Görükle, Bursa, Turkey. E-mail: ridvanali{at}uludag.edu.tr


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann OncolHome page
K. Prabhash, P. S. R. K. Sastry, G. Biswas, A. Bakshi, N. Prasad, H. Menon, and P. M. Parikh
Pregnancy outcome of two patients treated with imatinib
Ann. Onc., December 1, 2005; 16(12): 1983 - 1984.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.