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Japanese Journal of Clinical Oncology 34:280-281 (2004)
© 2004 Foundation for Promotion of Cancer Research

False-positive Finding on 18F-FDG PET after Chemotherapy for Primary Diffuse Large B-cell Lymphoma of the Thyroid: a Case Report

Maurizio Marchesi1, Marco Biffoni1 and Fausto Biancari2,+

1 Division of General Surgery, Department of Surgical Sciences, University ‘La Sapienza’, Rome, Italy and 2 Department of Surgery, University of Oulu, Oulu, Finland

Primary non-Hodgkin lymphoma of the thyroid is an uncommon disease. It is a potentially aggressive disease and diffuse large B-cell lymphoma of the thyroid may result in 5 year survival rates <50%. Hence adequate follow-up and multimodality treatment for recurrent or persistent disease are required. Since 18F-FDG PET is considered the imaging method of choice for the detection and staging of lymphoma, this was used for restaging of a case of diffuse large B-cell lymphoma of the thyroid after chemotherapy and its diagnostic value is questioned in the present case report. In fact, PET showed a false-positive finding which led to unnecessary surgery.

+ For reprints and all correspondence: Fausto Biancari, Department of Surgery, Oulu University Hospital, P.O. Box 21, 90029 Oulu, Finland. E-mail: faustobiancari{at}yahoo.it


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