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Japanese Journal of Clinical Oncology 2005 35(4):218-220; doi:10.1093/jjco/hyi056
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© 2005 Foundation for Promotion of Cancer Research

Case Report

Inflammatory Pseudotumor of the Liver in a Patient with Early Gastric Cancer: CT–Histopathological Correlation

Rieko Nishimura1, Hiroshi Mogami2, Norihiro Teramoto1, Minoru Tanada3 and Akira Kurita3

Departments of 1 Clinical Laboratory, 2 Radiology and 3 Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan

For reprints and all correspondence: Rieko Nishimura, Department of Clinical Laboratory, National Hospital Organization Shikoku Cancer Center, 13 Horinouchi, Matsuyama, Ehime, 790-0007 Japan. E-mail: rnishimu{at}shikoku-cc.go.jp

Received August 4, 2004; accepted November 20, 2004

A case of inflammatory pseudotumor (IPT) of the liver associated with early gastric cancer is reported. Intravenous contrast-enhanced computed tomography (CT) showed a large, irregularly shaped mass lesion in the left lobe of the liver. The lesion was characterized by peripheral rim-like or septal enhancement and an internal low density area in the delayed phase. The gastric cancer was a papillary adenocarcinoma limited to the mucosa. The resected liver tumor measured 5.5 x 5.0 x 4.0 cm, and its cut surface revealed a well-circumscribed mass divided into lobules by fibrous tissue. Histologically the mass was composed of fibrous areas and cellular areas, and the cellular areas consisted of fascicles of plump spindle cells intermingled with varying numbers of plasma cells, lymphocytes and histiocytes. Thus, the higher attenuation on the enhanced CT scan corresponded to the areas of intense fibrosis, and the areas of lower attenuation corresponded to the predominantly cellular areas. The CT findings of delayed peripheral rim-like or septal enhancement of the hepatic tumor may be a specific finding of IPT.

Key Words: hepatic inflammatory pseudotumor • enhanced CT • delayed enhancement • early gastric cancer


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