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Japanese Journal of Clinical Oncology Advance Access originally published online on October 27, 2006
Japanese Journal of Clinical Oncology 2006 36(11):731-734; doi:10.1093/jjco/hyl101
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© 2006 Foundation for Promotion of Cancer Research

Metastatic Non-Small-Cell Lung Carcinoma Successfully Treated with Pre-operative Chemotherapy and Bilateral Adrenalectomy

Alberto Muñoz1,, Guillermo López-Vivanco1, Joan-Manel Mañé1, Ricardo Fernández1, Javier Díaz-Aguirregoitia2, Mónica Saiz3 and Ramón Barceló1

1 Department of Medical Oncology
2 Department of Surgery, Unit of Endocrine Surgery
3 Department of Pathology, Hospital de Cruces, Osakidetza, Basque Country, Spain

For reprints and all correspondence: Alberto Muñoz, Plaza de Cruces s/n, 48903 Barakaldo, Basque Country, Spain. E-mail: amunoz{at}hcru.osakidetza.net

Received December 18, 2005; accepted July 15, 2006

Metastatic non-small-cell lung cancer is a common condition with a dismal prognosis. Although palliative chemotherapy improves survival and quality of life, nearly all patients die of progressive disease. Metastatic involvement of adrenal glands is not rare, but usually reflects widespread dissemination. Selected patients with single adrenal metastasis may be cured with surgery, although the level of evidence comes from single cases reports and short retrospective series. Here we report a patient with bilateral adrenal metastases from previously resected non-small-cell lung cancer, who remains free of disease four years after pre-operative chemotherapy and bilateral adrenalectomy.

Key Words: non-small-cell lung carcinoma • chemotherapy • surgery • adrenalectomy


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