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Japanese Journal of Clinical Oncology Advance Access originally published online on July 14, 2006
Japanese Journal of Clinical Oncology 2006 36(9):598-601; doi:10.1093/jjco/hyl059
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© 2006 Foundation for Promotion of Cancer Research


Case Report

Distant Metastasis of Prostate Cancer: Early Detection of Recurrent Tumor with Dual-Phase Carbon-11 Choline Positron Emission Tomography/Computed Tomography in Two Cases

Tetsuo Maeda1, Ukihide Tateishi1, Motokiyo Komiyama2, Hiroyuki Fujimoto2, Shun-Ichi Watanabe3, Takashi Terauchi4, Noriyuki Moriyama4, Yasuaki Arai1, Kazuro Sugimura5 and Tadao Kakizoe2

1 Division of Diagnostic Radiology, 2 Division of Urology, 3 Division of Thoracic Surgery, National Cancer Center Hospital, 4 Division of Cancer Screening, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo and 5 Department of Diagnostic Radiology, Kobe University Graduate School of Medicine, Kobe, Japan

For reprints and all correspondence: Ukihide Tateishi, Division of Diagnostic Radiology, National Cancer Center Hospital, Tsukiji, Chuo-ku 104-0045, Tokyo, Japan. E-mail: utateish{at}ncc.go.jp

Received April 4, 2006; accepted May 1, 2006

Several types of recurrence may be detected by radiologic assessment after treatment in patients with prostate cancer. However, early detection of distant metastasis using positron emission tomography has so far never been published. We report two patients who underwent hormone therapy or surgical resection for prostate cancer. They developed distant metastases which were detected on whole body [C-11] choline positron emission tomography/computed tomography with significant elevation of serum PSA level. In one patient, recurrent tumor of the supraclavicular node (6 mm) diminished in size after subsequent hormone therapy. Surgical resection of recurrent tumor of the lung (12 mm) was performed in the other patient, the pathology of which confirmed the metastatic adenocarcinoma derived from the prostate. The recurrent tumor can be correctly detected by dual-phase whole body [C-11] choline positron emission tomography/computed tomography.

Key Words: prostate cancer • carbon-11 choline • positron emission tomography • computed tomography


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T. Terauchi, U. Tateishi, T. Maeda, D. Kanou, H. Daisaki, Y. Moriya, N. Moriyama, and T. Kakizoe
A Case of Colon Cancer Detected by Carbon-11 Choline Positron Emission Tomography/Computed Tomography: An Initial Report
Jpn. J. Clin. Oncol., October 1, 2007; 37(10): 797 - 800.
[Abstract] [Full Text] [PDF]



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