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Japanese Journal of Clinical Oncology 2008 38(1):78-83; doi:10.1093/jjco/hym148
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© The Authors (2008). Published by Oxford University Press. All rights reserved

Possible Impact of the NHK Special Questioning Cancer Treatment in Japan on Clinicians' Prescriptions of Oxaliplatin

Tomoko Matsumura1, Koichiro Yuji2, Toshihito Nakamura1,3, Fumitaka Beppu4, Eiji Kusumi1, Tamae Hamaki1,, Kazuhiko Kobayashi1, Yukiko Kishi5, Mutsuko Onishi6, Yuko Kodama1, Yuji Tanaka1 and Masahiro Kami1,

1 Division of Exploratory Research, Institute of Medical Science, University of Tokyo, Tokyo, Japan
2 Department of Internal Medicine, Institute of Medical Science, University of Tokyo, Tokyo, Japan
3 Department of Hematology and Oncology, Graduate School of Medicine and Hospital, University of Tokyo, Tokyo, Japan
4 Division of Social Medicine, Department of Healthcare Systems Research, Hokkaido University Graduate School of Medicine, Hokkaido, Japan
5 Division of Regenerative Medicine, Jichi Medical School, Tochigi, Japan
6 Institute for Health Promotion and Disease Prevention Research (IPR), Keck School of Medicine, University of Southern California, CA, USA

For reprints and all correspondence: Masahiro Kami, Department of Hematology and Oncology, Graduate School of Medicine and Hospital, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. E-mail: kami-tky{at}umin.ac.jp

Received September 3, 2007; accepted October 12, 2007

Medical information through media may influence physicians' prescriptions of medication. The Japan Broadcasting Corporation (NHK) aired on April and May 2005, a special program called ‘Questioning Cancer Treatment in Japan’, covering oxaliplatin. We investigated potential impact of this program on prescriptions, utilizing a post-marketing clinical trial monitoring of all patients receiving oxaliplatin. The post-marketing clinical trial reached the target sample size of 1200 by the 4th week of May, 44 weeks sooner than anticipated. The newly registered numbers of facilities and patients exhibited a bimodal peak in April and June. The viewer rating of NHK special was 8.3%, whereas three national newspapers and one weekly magazine took up the minor articles of oxaliplatin. In July 2007, 405 clinicians sent a written opinion to NHK, stating ‘NHK special invites misperceptions and confusions to public.’ NHK special might have had an impact on clinicians' prescriptions of oxaliplatin.

Key Words: oxaliplatin • television program • post-marketing clinical trial • colon cancer


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