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Japanese Journal of Clinical Oncology Advance Access originally published online on June 26, 2008
Japanese Journal of Clinical Oncology 2008 38(7):501-503; doi:10.1093/jjco/hyn055
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© The Author (2008). Published by Oxford University Press. All rights reserved

Phase II Study of Laparoscopy-assisted Distal Gastrectomy with Nodal Dissection for Clinical Stage I Gastric Cancer: Japan Clinical Oncology Group Study JCOG0703

Yukinori Kurokawa1, Hitoshi Katai2, Haruhiko Fukuda3, Mitsuru Sasako4 for the Gastric Cancer Surgical Study Group of the Japan Clinical Oncology Group

1 Department of Surgery, Osaka National Hospital, Osaka
2 Gastric Surgery Division, National Cancer Center Hospital, Tokyo
3 Center for Cancer Control and Information Services, National Cancer Center, Tokyo
4 Department of Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

For reprints and all correspondence: Hitoshi Katai, Gastric Surgery Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. E-mail: hkatai{at}ncc.go.jp

Received February 20, 2008; accepted June 2, 2008

A phase II trial was started in Japan to evaluate the safety of laparoscopy-assisted distal gastrectomy (LADG) for clinical stage I gastric cancer. A total of 170 patients will be enrolled in this study by expert surgeons for laparoscopy from 16 institutions over 1 year. The primary endpoint is incidence of anastomotic leak and pancreatic fistula. The secondary endpoints are overall survival, relapse-free survival, proportion of completion of LADG, proportion of conversion from LADG to open gastrectomy, surgical morbidity and short-term clinical outcomes.

Key Words: gastric cancer • laparoscopy assisted gastrectomy • phase II study


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