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Japanese Journal of Clinical Oncology 9:225-232 (1979)
© 1979 Foundation for Promotion of Cancer Research

research-article

Diagnostic Value of 201Tl-chloride Scintigraphy for Thyroid Tumors

OSAMU SENGA, M.D., MAKOTO MIYAKAWA, M.D., MASAO MAKIUCHI, M.D., RIKIO FURIHATA, M.D., MASANORI MIYAZAWA, M.D.* and MASAOMI TAKIZAWA, M.D.*

Department of Surgery, Faculty of Medicine, Shinshu University Matsumoto
*Department of Radiological Sciences, Shinshu University Hospital Matsumoto

Received June 21, 1979; Among 114 patients with thyroid disease examined by 201Tl-chloride scintigraphy, 101 were given a histological diagnosis. Of 28 cases of thyroid carcinoma, 22 (78.6%) were positive. In three of the 22, an obvious accumulation of 201Tl-chloride was revealed in the metastatic lymph nodes of the neck and mediastinum.

Only 12 of 50 (24%) cases of thyroid adenoma were positive. In comparison, all cases of hyperthyroidism and chronic thyroiditis were positive and all cases of subacute thyroiditis were negative. The histological types of thyroid tumor were examined. Of 22 cases of papillary carcinoma, 18 (81.8%) were positive. In four cases which revealed negative figures, the tumor was almost completely encysted in three and the tumor was small in the other. Of the adenomas, eight cases of tubular adenoma and three of trabecular adenoma were all positive, but colloid adenoma and thyroid cyst cases were all negative.

It was concluded that 201Tl-chloride has no specific affinity for malignant tumors and cannot be used to discriminate between carcinoma and adenoma, but surgery should be indicated for nodules which are positive scanning by 201Tl-chloride.


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