Skip Navigation



Japanese Journal of Clinical Oncology Advance Access published online on July 24, 2007
Japanese Journal of Clinical Oncology, doi:10.1093/jjco/hym058
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
37/7/534    most recent
hym058v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Matsubara, A.
Right arrow Articles by Usui, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matsubara, A.
Right arrow Articles by Usui, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2007 Foundation for Promotion of Cancer Research

Lower Urinary Tract Symptoms after Radical Perineal Prostatectomy

Akio Matsubara1,, Tatsuaki Yoneda2, Hiroaki Yasumoto1, Jun Teishima1, Hiroaki Shiina2, Mikio Igawa2, Koji Mita1 and Tsuguru Usui1

1 Department of Urology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima
2 Department of Urology, Shimane University School of Medicine, Izumo, Shimane Japan

For reprints and all correspondence: A. Matsubara, Department of Urology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. E-mail: matsua{at}hiroshima-u.ac.jp

Received January 18, 2007; accepted February 24, 2007

Objective: To clarify the impact of radical perineal prostatectomy (RPP) on lower urinary tract symptoms (LUTS) in patients with clinically localized prostate cancer.

Methods: A total of 117 patients with a median age of 69 years who underwent RPP alone between August 2002 and August 2005 were included in the study. We measured LUTS on the basis of the International Prostate Symptom Score (IPSS) and IPSS quality of life (QOL) questionnaire before, and 3, 6 and 12 months after surgery.

Results: The overall mean total IPSS and IPSS QOL score decreased over time after RPP and was significantly reduced at 12 months after surgery. The decrease of the score was more prominent and rapid in patients with moderate to severe symptoms (IPSS ≥ 8), whereas in those with no or only mild symptoms (IPSS ≤ 7), the score did not change significantly after RPP. When the patients were divided into groups with baseline scores of 0–1 and 2–5 for each of the seven composites of the IPSS, scores for the 2–5 group improved significantly after RPP in all composites, whereas the 0–1 group had significantly worse scores for voiding frequency and nocturia. No significant change was noted in any of the other five composites.

Conclusion: This longitudinal study shows that RPP is significantly beneficial for moderate to severe LUTS, but also has adverse effects on voiding frequency and nocturia in some men with no or mild symptoms. This information is important when counseling patients about treatment options for localized prostate cancer.

Key Words: prostate cancer • radical perineal prostatectomy • lower urinary tract symptoms


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.