Skip Navigation



Japanese Journal of Clinical Oncology Advance Access published online on October 17, 2007
Japanese Journal of Clinical Oncology, doi:10.1093/jjco/hym107
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
37/10/750    most recent
hym107v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Onishi, T.
Right arrow Articles by Sugimura, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Onishi, T.
Right arrow Articles by Sugimura, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2007 Foundation for Promotion of Cancer Research

Assessment of Health-related Quality of Life after Radiofrequency Ablation or Laparoscopic Surgery for Small Renal Cell Carcinoma: a Prospective Study with Medical Outcomes Study 36-Item Health Survey (SF-36)

Takehisa Onishi1,3, Kouhei Nishikawa1, Yoshihiro Hasegawa1, Yasushi Yamada1, Norihito Soga1, Kiminobu Arima1, Koichiro Yamakado2, Akira Hoshina3 and Yoshiki Sugimura1

1 Division of Nephro-Urologic Surgery and Andrology
2 Division of Radiology, Department of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Tsu
3 Department of Urology, Yamada Red Cross Hospital, Ise, Mie, Japan

For reprints and all correspondence: Takehisa Onishi, Department of Urology, Yamada Red Cross Hospital, 810 Takabuku, Misono, Ise, Mie, Japan, 516-0805, Japan. E-mail: takehisa{at}yamada.jrc.or.jp

Received March 23, 2007; accepted June 24, 2007

Objective: The purpose of this study was to assess the changes in health-related quality of life (HRQoL) during follow-up period in patients treated with percutaneous radiofrequency ablation (RFA) or laparoscopic surgery for small renal cell carcinoma.

Methods: From December 2004 through September 2006, for 37 consecutive patients, who were diagnosed with renal cell carcinoma and underwent percutaneous RFA (n = 20) or laparoscopic radical nephrectomy (n = 17) at our institution. HRQoL was evaluated prospectively using SF-36 Health survey pre- and post-operatively (1, 4, 12 and 24 weeks after surgery).

Results: Four of the eight scale scores of SF-36 were significantly lower pre-operatively in the RFA group than in the laparoscopic surgery group. The QoL scores in physical functioning, role-physical functioning and role-emotional functioning were significantly reduced one week after laparoscopic surgery. However, there was no reduction of the SF-36 QoL scores one week after operation in the RFA group. Furthermore, HRQoL scores in the RFA group showed a tendency to improve during follow-up periods.

Conclusions: This is the first study to evaluate HRQoL changes (up to 24 weeks) in patients who have undergone RFA or laparoscopic radical nephrectomy for small renal cell carcinoma. No reduction, but rather an improvement, in HRQoL was seen in the RFA group during follow-up periods. From the point of view of QoL, RFA could be a viable alternative treatment for selected patients with small renal cell carcinoma.

RFA could be a viable alternative treatment for the selected patients with small renal cell carcinoma

Key Words: quality of life • renal cell carcinoma • radiofrequency ablation • laparoscopic surgery


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 RadiologyHome page
P. V. Pandharipande, D. A. Gervais, P. R. Mueller, C. Hur, and G. S. Gazelle
Radiofrequency Ablation versus Nephron-sparing Surgery for Small Unilateral Renal Cell Carcinoma: Cost-effectiveness Analysis
Radiology, July 1, 2008; 248(1): 169 - 178.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.