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Japanese Journal of Clinical Oncology Pages 57

Editorial
Editorial: Antiemetic Therapy

Antiemetic Therapy

Nagahiro Saijo, Medical Oncology Division, National Cancer Center Hospital, Tokyo

Nausea and vomiting are the most problematic adverse drug reactions in patients receiving chemotherapy. The grade of drug-induced emesis depends mainly on the intrinsic emetogenicity of the drug although the dose of the drug and host factors such as age, sex, food, etc. relates with the severity and incidence of emesis. Cisplatin has been demonstrated to be one of the most effective chemotherapeutic agents against a variety of solid tumors. However, it has a strong emetic effect and some patients refuse . . . [Full Text of this Article]


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