Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Kranenbarg, E.
Right arrow Articles by van de Velde, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kranenbarg, E.
Right arrow Articles by van de Velde, C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Japanese Journal of Clinical Oncology Pages 185-186

Editorial
Introduction
Standardization
Quality Control
Trial Participation
Conclusions
References
Editorial: Importance of Organizing Surgical Trials in Oncology

Editorial: Importance of Organizing Surgical Trials in Oncology

Elma Klein Kranenbarg and Cornelis J. H. van de Velde

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands

INTRODUCTION

The first randomized clinical trial was carried out fifty years ago, when the efficacy of streptomycin in the treatment of tuberculosis was demonstrated (1). Since then, many, mainly medical, randomized trials have been conducted. The contribution of surgical randomized trials has been relatively low, although results from randomized trials are the only results used for `evidence based medicine'. In 1996, Richard Horton, editor of the Lancet, wrote a commentary entitled `surgical research or comic opera: questions, but few answers' (2). He reported that only 7% of papers published in nine general surgery journals were randomized trials and almost half of the publications were case studies and he therefore concluded . . . [Full Text of this Article]

STANDARDIZATION

QUALITY CONTROL

TRIAL PARTICIPATION

CONCLUSIONS

References


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?