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Japanese Journal of Clinical Oncology Pages 243-244

Editorial
Editorial: How to manage metastatic brain tumors

How to manage metastatic brain tumors

Soichiro Shibui, Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan

The frequency of metastatic brain tumors is increasing. Non-invasive examination such as computed tomography and magnetic resonance imaging makes it possible to detect brain metastases even in seriously ill patients. Moreover, the number of long survivors are increasing by the development of effective anti-cancer treatments for primary cancers and 20-40% of cancer patients are reported to have brain metastases at autopsy. Prognosis of patients with brain metastases has been very poor and radiotherapy to the whole brain has been a main and unique treatment until recently. Since 1990 several randomized studies have revealed the importance of surgical removal of brain metastases. Patchel et al. compared the survival time after treatment and the recurrence rate . . . [Full Text of this Article]


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