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Japanese Journal of Clinical Oncology Pages 403-405

An Analysis of Institutional Effects in a Multicenter Cancer Clinical Trial: is it also Plausible from the Clinicians' Point of View?
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An Analysis of Institutional Effects in a Multicenter Cancer Clinical Trial: is it also Plausible from the Clinicians' Point of View?

An Analysis of Institutional Effects in a Multicenter Cancer Clinical Trial: is it also Plausible from the Clinicians' Point of View?

Junichi Sakamoto1, Yutaka Matsuyama2 and Yasuo Ohashi2

1Department of Surgery and Laboratory of Clinical Oncology, Aichi Prefectural Hospital, Okazaki, Aichi and 2Department of Biostatics/Epidemiology and Preventive Health Sciences, School of Health Science and Nursing, The University of Tokyo, Tokyo, Japan

The institutional effect is a somewhat delicate issue in randomized clinical trials. Despite eager attempts to standardize the methods of diagnosis and treatment among participating institutions, it is still difficult to assert that such criteria could be applied equally not only . . . [Full Text of this Article]

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