Japanese Journal of Clinical Oncology 31:571-572 (2001)
© 2001 Foundation for Promotion of Cancer Research
Editorial |
Is Peritoneal Carcinomatosis an Incurable Disease or Controllable Locoregional Condition? Challenge of Surgeons with Intraperitoneal Hyperthermic Chemotherapy
Gastric Surgery Division, National Cancer Center Hospital, Tokyo, Japan
Peritoneal carcinomatosis is the most common terminal feature of abdominal cancers. For gastrointestinal surgeons and medical oncologists, it is a vexing condition because, although the disease is limited to the peritoneal surface, complete surgical removal is impossible and systemic chemotherapy is powerless. Peritoneal carcinomatosis is generally considered to be an untreatable condition that makes clinicians abandon further aggressive treatments.
Gynecologists have some different views on ovarian cancer. They have tried extensive debulking surgery for the peritoneal disease followed by intraperitoneal (i.p.) cisplatin-based chemotherapy. A large, randomized controlled trial has recently shown significant survival benefit of
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