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Japanese Journal of Clinical Oncology 2007 37(10):801; doi:10.1093/jjco/hym140
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© 2007 Foundation for Promotion of Cancer Research

A Case of Recurrent Gastric Carcinoid Tumor

Makoto Saka

Gastric Surgery Division
National Cancer Center Hospital
Tokyo, Japan

A 68-year-old woman was diagnosed as having a small gastric tumor in an annual health check. Gastroduodenoscopy revealed a flat-elevated mucosal tumor, measuring 6 mm in diameter, on the posterior wall of the fornix (Fig. 1; please note that a color version of this figure is available as supplementary data at http://www.jjco.oxfordjournals.org). Biopsy of the lesion revealed typical carcinoid tumor (Fig. 2; please note that a color version of this figure is available as supplementary data at http://www.jjco.oxfordjournals.org), and this lesion was removed by endoscopic mucosal resection (EMR). In the pathological examination, the resected specimen showed massive submucosal invasion. Immunohistochemical study revealed MIB-1 labeling index of 30%, suggesting a high risk of nodal metastasis. Thus, we performed proximal gastrectomy with lymphadenectomy, but there was no lymph node metastasis.


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Three years after EMR, follow-up CT scan demonstrated multiple hepatic metastases. She underwent transarterial chemoembolization using CDDP two times and is still alive with disease for 8 months after detection of the recurrence.


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This Article
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