Skip Navigation

Japanese Journal of Clinical Oncology 2008 38(12):871; doi:10.1093/jjco/hyn137
This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Supplementary Data
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Suzuki, H.
Right arrow Articles by Saito, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Suzuki, H.
Right arrow Articles by Saito, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© The Author (2008). Published by Oxford University Press. All rights reserved

Autofluorescence and Narrow-band Imaging Endoscopy for Detecting Early-staged Cancer in Barrett's Esophagus: A Case Report

Haruhisa Suzuki and Yutaka Saito

Division of Endoscopy,
National Cancer Center Hospital,
Tokyo, Japan

A 74-year-old man was referred to our hospital for the treatment of an esophageal lesion. Conventional endoscopy revealed a slight reddish area in long-segment Barrett's esophagus, but the margin of the lesion could not be visualized clearly (Figs 1 and 2; note that colour versions of all the figures are available as supplementary data at http://www.jjco.oxfordjournals.org). Using the autofluorescence imaging (AFI) mode, the lesion was delineated clearly as a purple area on a green background mucosa (Fig. 3). Subsequent detailed inspection by narrow-band imaging (NBI) with magnification showed irregular mucosal and vascular patterns and presence of abnormal blood vessels, which suggested early-staged neoplasia in Barrett's esophagus (Fig. 4). Biopsy specimens of this lesion revealed adenocarcinoma.


Figure 1
View larger version (136K):
[in this window]
[in a new window]
[Download PowerPoint slide]
  		Figure 1.
 

Figure 2
View larger version (144K):
[in this window]
[in a new window]
[Download PowerPoint slide]
  		Figure 2.
 

Figure 3
View larger version (116K):
[in this window]
[in a new window]
[Download PowerPoint slide]
  		Figure 3.
 

Figure 4
View larger version (127K):
[in this window]
[in a new window]
[Download PowerPoint slide]
  		Figure 4.
 
We performed endoscopic submucosal dissection for this lesion. The resected specimen revealed well-differentiated adenocarcinoma with low-grade atypia that was confined to the mucosal layer without lymphatic or venous infiltration. The tumor extension was histopathologically equal to the purple area depicted with AFI. On assessment of early-staged neoplasia in Barrett's esophagus, AFI could be one of the useful techniques to identify the suspicious lesions followed by NBI with magnification.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?



This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Supplementary Data
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Suzuki, H.
Right arrow Articles by Saito, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Suzuki, H.
Right arrow Articles by Saito, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?