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Japanese Journal of Clinical Oncology 2009 39(1):70; doi:10.1093/jjco/hyn149
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© The Author (2008). Published by Oxford University Press. All rights reserved

A Case of Locally Advanced Chondroblastoma in the Proximal Humerus

Fumihiko Nakatani and Yasuo Beppu

Musculoskeletal Oncology Division
National Cancer Center Hospital
Tokyo, Japan

A 13-year-old male was referred to our institute presenting with a large mass and pain in his left shoulder. Magnetic resonance imaging (MRI) demonstrated a huge tumor in the left proximal humerus, which destroyed the anterior part of humeral head (Fig. 1). The tumor protruded into his left shoulder joint resulting in the increase of the articular fluid (Fig. 2, arrow heads). Needle biopsy specimens were composed of matrix-rich and cellular areas. The matrix-rich area was made up of chondroid, osteoid and fibrous cartilage matrices. Round or polygonal tumor cells, which exhibited eosinophilic cytoplasm and ovoid-shaped nucleus, were arranged homogenously (Fig. 3; note that a color version of this figure is available as supplementary data at http://www.jjco.oxfordjournals.org). Considering the radiological and pathological findings, we diagnosed the tumor as locally advanced benign chondroblastoma.


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We performed transcatheter arterial embolization of tumor vessels using coils and gelatin foam powder before surgery to decrease the intraoperative bleeding. On the next day after the embolization, we conducted tumor curettage followed by artificial and autologous bone transplantation. Six months after surgery, the patient was back to the school life with acceptable motion range limitation of his left shoulder.


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This Article
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Right arrow Supplementary Data
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