© The Author (2009). Published by Oxford University Press. All rights reserved
A Case of Bilateral Retinoblastoma with Left Orbital Cellulitis
Ophthalmology Division
National Cancer Center Hospital,
Tokyo, Japan
A 5-month-old boy was referred to our hospital for the treatment of left eyelid swelling and leukocoria. His left eyelid was swollen and could not be opened by himself. The conjunctiva was also swollen, and the cornea was clouded because of increased intraocular pressure. Orbital CT scan demonstrated a left intraocular tumor with calcification, periocular high-intensity area (anterior orbital cellulitis) and deformed eyeball (Fig. 1). The intraocular tumor showed low signal intensity on T2-weighted image. His right eye had three small retinal tumors, and the clinical diagnosis was bilateral retinoblastoma. His left eye was enucleated, and the pathological examination revealed retinoblastoma with calcification and extensive necrosis, however, without extraocular extension (Fig. 2; note that a color version of this figure is available as supplementary data at http://www.jjco.oxfordjournals.org). He underwent no systemic chemotherapy, but only selective ophthalmic arterial injection for the right eye.
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Orbital cellulitis is rare in patients with intraocular retinoblastoma. Because it does not always caused by extraocular tumor extension, pathological confirmation is very important for determining the indication of adjuvant therapy.
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