Japanese Journal of Clinical Oncology 18:195-201 (1988)
© 1988 Foundation for Promotion of Cancer Research
research-article |
The Incidence of Secondary Tumors of the Heart and Pericardium: A 10-Year Study
1Pathology Division, National Cancer Center Research Institute 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104
2Internal Medicine, National Cancer Center Hospital 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104
* For reprints and all correspondence
Received December 25, 1987; accepted March 10, 1988
Secondary tumors of the heart and pericardium are much more common than primary tumors. During a 10-year period (1976–1985), only one instance of a primary tumor (malignant mesothelioma) was identified among 2,649 autopsies of malignant tumors at the National Cancer Center Hospital. In contrast, there were 407 cases in which heart and/or pericardium were secondarily involved with a malignant tumor from other organs. In 78 cases, the secondary tumors were present only in the pericardium, while in 329 cases, the tumors involved the heart itself with or without pericardial involvement. Among the primary tumors, three-quarters were carcinomas of various organs. In addition there were 53 hematologic malignancies, 19 melanomas and 17 sarcomas. In 31 cases, cardiac failure was the direct cause of death. The secondary tumors of the heart were often overlooked clinically because the cardiac dysfunction appeared to be part of the deteriorating general condition. Electrocardiography and echocardiography were often helpful in suggesting the presence of cardiac metastases. Appropriate diagnostic procedures and therapeutic intervention should be considered for the care of patients with advanced malignancy and sudden onset of cardiac failure.
Key Words: Heart • Pericardium • Metastatic tumors • Electrocardiography • Echocardiography
3Current address: Internal Medicine, Tochigi Cancer Center, Utsunomiya.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  N. Samiei, M. M. Farahani, A. Sadeghipour, K. Mozaffari, and M. Maleki Intracardiac metastasis of malignant melanoma Eur J Echocardiogr, May 1, 2008; 9(3): 393 - 394. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. G. Spiro, M. K. Gould, and G. L. Colice Initial Evaluation of the Patient With Lung Cancer: Symptoms, Signs, Laboratory Tests, and Paraneoplastic Syndromes: ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition) Chest, September 1, 2007; 132(3_suppl): 149S - 160S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A D Borsaru, K K Lau, and P Solin Cardiac metastasis: a cause of recurrent pulmonary emboli Br. J. Radiol., February 1, 2007; 80(950): e50 - e53. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R Bussani, F De-Giorgio, A Abbate, and F Silvestri Cardiac metastases J. Clin. Pathol., January 1, 2007; 60(1): 27 - 34. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Beckles, S. G. Spiro, G. L. Colice, and R. M. Rudd Initial Evaluation of the Patient With Lung Cancer: Symptoms, Signs, Laboratory Tests, and Paraneoplastic Syndromes Chest, January 1, 2003; 123(1_suppl): 97S - 104S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Maisch, A.D. Ristic, S. Pankuweit, A. Neubauer, and R. Moll Neoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatin Eur. Heart J., October 2, 2002; 23(20): 1625 - 1631. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kudo, F. Yamasaki, Y. Doi, and T. Sugiura clinical correlates of pr-segment depression in asymptomatic patients with pericardial effusion J. Am. Coll. Cardiol., June 19, 2002; 39(12): 2000 - 2004. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Chiles, P. K. Woodard, F. R. Gutierrez, and K. M. Link Metastatic Involvement of the Heart and Pericardium: CT and MR Imaging RadioGraphics, March 1, 2001; 21(2): 439 - 449. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P.-C. Wang, K.-Y. Yang, J.-Y. Chao, J. M. Liu, R.-P. Perng, and S.-H. Yen Prognostic Role of Pericardial Fluid Cytology in Cardiac Tamponade Associated With Non-small Cell Lung Cancer Chest, September 1, 2000; 118(3): 744 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Barasch, R. Hariharan, P. F. Wong, and K. A. Heck Pleural and Pericardial Effusions in a 50-Year-Old Woman Circulation, June 15, 1996; 93(12): 2197 - 2202. [Full Text]
|
|