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Japanese Journal of Clinical Oncology, Vol 27, Issue 2 111-114, Copyright © 1997 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

Colonoscopy for frank bloody stools associated with cancer chemotherapy

T Yokoyama, H Kondo, T Yokota, Y Tokue, D Saito, Y Shimada and K Sugihara
Department of Endoscopy, National Cancer Center Hospital, Tokyo, Japan.

Diarrhea is a common complication of cancer chemotherapy, while bloody stool is rare. Pseudomembranous colitis has been reported as causing bloody diarrhea after chemotherapy. In this report, we describe nine consecutive patients who presented frank bloody stools within one month after cancer chemotherapy. Patients with a history of pelvic irradiation or with a previously identified colorectal tumor were excluded. Among nine patients, bleeding from tumor undetected before chemotherapy was seen in three, pseudomembranous colitis in four, ischemic colitis in one and methicillin-resistant Staphylococcus aureus enterocolitis in one. Of the three tumors, one was an adenomatous polyp and the other two were metastatic tumors. Two of the four patients with pseudomembranous colitis had not received antibiotics before the onset of colitis. Causes of bloody stools after chemotherapy were various and colonoscopy played an important role in diagnosis and prompt therapy.
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 J Oncol Pharm PractHome page
G. Richardson and R. Dobish
Chemotherapy induced diarrhea
Journal of Oncology Pharmacy Practice, December 1, 2007; 13(4): 181 - 198.
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