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Japanese Journal of Clinical Oncology, Vol 27, Issue 6 442-444, Copyright © 1997 by Foundation for Promotion of Cancer Research

ORIGINAL ARTICLE

Combination chemotherapy using intravenous nedaplatin (254-S) and intraarterial cisplatin (CDDP) with transcatheter arterial embolization (TAE) for a patient with uterine cervical cancer: a case report

S Adachi, N Yamasaki, T Ogasawara, Y Takayasu, T Takemura and K Koyama
Department of Obstetrics and Gynecology, Hyogo College of Medicine, Japan.

A 45-year-old Japanese woman with a bulky (75 x 40 mm) stage 2a uterine cervical cancer was treated with 87 mg (50 mg/m2) of nedaplatin (254-S) intravenously and 120 mg (70 mg/m2) of cisplatin (CDDP) intraarterially with transcatheter arterial embolization (TAE). She received three courses of this combination chemotherapy and showed a complete response, as confirmed by magnetic resonance imaging. A radical hysterectomy was performed and the pathological findings revealed the absence of carcinoma cells. This type of combination chemotherapy seems to be effective for the treatment of locally advanced uterine cervical cancer.
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