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Japanese Journal of Clinical Oncology Pages 117-118

Progress in Cell Therapy in Japan 1999
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Progress in Cell Therapy in Japan 1999

Progress in Cell Therapy in Japan 1999

Yoichi Takaue and Ryuji Tanosaki

Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan

Collection of mobilized peripheral blood hematopoietic stem cell (PBSC) is easily applicable without the risk of anesthesia or invasive multiple marrow aspirations, since this can be accomplished by a little modifying apheresis technique that is routinely used at blood centers for the collection of single donor platelets. Use of PBSC results in rapid and durable trilineage hematopoietic recovery after myeloablative chemotherapy, and replaces bone marrow transplantation (BMT). Time-intense collective procedure of PBSC to bring additional workload to therapeutic unit used to be a major setback of PBSC transplantation (PBSCT). However, marked improvement in the collection procedure with the use of granulocyte colony-stimulating factor (G-CSF) has made the procedure far more simpler, by decreasing the number of apheresis. This also . . . [Full Text of this Article]

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