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Japanese Journal of Clinical Oncology Pages 272-274

Letter
Introduction
Development of a trial design
Instruction and quality control
Start of the trial
Conclusions
References
Letter: Practical Information on the Conduct of Randomized Trials. An Example from The Netherlands

Practical Information on the Conduct of Randomized Trials. An Example from The Netherlands

To the Editor:

In the April 1999 issue of the Japanese Journal of Clinical Oncology we stressed the importance of organizing surgical trials in oncology (1). Through our collaboration with Japanese surgeons we have understood that in Japan there is not a lot of enthusiasm among clinicians to perform or participate in clinical trials. This is demonstrated, for example, by a randomized trial comparing D2 and D3 dissection in rectal cancer which did not succeed. In Japan, there is one independent well organized trial organization, the Japanese Clinical Oncology Group, however, its capacity is limited and additional governmental support is not to be expected.

The same low trial ambiance exists for example in France. French surgeons, particularly . . . [Full Text of this Article]

INTRODUCTION

DEVELOPMENT OF A TRIAL DESIGN

INSTRUCTION AND QUALITY CONTROL

START OF THE TRIAL

CONCLUSIONS

References


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