Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (17)
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Tomaru, U.
Right arrow Articles by Shimoda, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tomaru, U.
Right arrow Articles by Shimoda, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Japanese Journal of Clinical Oncology 30:313-317 (2000)
© 2000 Foundation for Promotion of Cancer Research

Primary Extracranial Meningioma of the Foot: A Case Report

Utano Tomaru1, Tadashi Hasegawa2, Fumio Hasegawa3, Masashi Kito4, Takanori Hirose5 and Tadakazu Shimoda1,+

1Clinical Laboratory, 2Pathology and 4Orthopedic Divisions and 3Electron Microscopy Laboratory, National Cancer Center Hospital and Research Institute, Tokyo and 5Department of Pathology, Saitama Medical School, Saitama, Japan

We present a rare case of primary extracranial meningioma in a 36-year-old man, who had a solitary multinodular mass located in the plantar muscle of the foot. The histology of specimens from simple excision was typical of meningioma, showing bland spindle cell proliferation with a whorl pattern. Immunohistochemical analysis demonstrated that the tumor cells showed diffuse and strong positivity for epithelial membrane antigen as well as moderate reactivity for cytokeratin and vimentin. Ultrastructurally, the tumor cells were characterized by thin bipolar cytoplasmic processes and joined by multiple small desmosomes. There were frequent pinocytotic vesicles and a distinct external lamina on the cell surface. These findings suggest that this primary ectopic meningioma, arising in the soft tissue, may have been derived from perineurial cells of the peripheral nerve, but was morphologically distinguishable from perineurioma. Primary extracranial meningioma should be included in the differential diagnosis of soft-tissue spindle cell tumors, especially those of peripheral nerve origin.

+ For reprints and all correspondence: Tadashi Hasegawa, Pathology Division, National Cancer Center Research Institute, 1–1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan. E-mail: tdhasega@gan2.ncc.go.jp


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur. J. Cardiothorac. Surg.Home page
X. Yang, X. Gao, and S. Wang
Primary mediastinal malignant meningioma
Eur. J. Cardiothorac. Surg., July 1, 2009; 36(1): 217 - 218.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. Palimento and M. Picchio
Meningioma of the mediastinum causing spontaneous hemothorax.
Ann. Thorac. Surg., May 1, 2006; 81(5): 1903 - 1904.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.