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Japanese Journal of Clinical Oncology 31:444-446 (2001)
© 2001 Foundation for Promotion of Cancer Research

Invasive Lobular Carcinoma of the Male Breast: a Case Report

Mehmet Koc1, Sitki Öztas2, M. Tülin Erem1, M. Akif Ciftcioglu3 and M. Derya Onuk4,+

1Department of Radiation Oncology, 2Department of Genetics and 4Department of Internal Medicine, Medical Faculty, Atatürk University, Erzurum and 3Department of Pathology, Medical Faculty, Akdeniz University, Antalya, Turkey

A case of lobular carcinoma in a male breast is described. Because the structure of the male breast does not have lobules and acini, lobular carcinoma cases are seen infrequently. The pathological diagnosis was invasive lobular carcinoma of the breast. The karyotype of the patient revealed a 46 XY/46 XY, dmin (double minutes) chromosomal structure. Although 28% of the examined metaphases showed 46 XY, 1–5 dmin, the others were normal. We reviewed the English literature and found 20 reported cases of lobular carcinoma of the male breast. Our case represents lobular carcinoma in a proven genotypic male patient showing no exogenous or endogenous estrogens.

+ For reprints and all correspondence: Mehmet Koc, Atatürk Universitesi Tip Fakültesi Radyasyon Onkolojisi Anabilim Dali, 25240 Erzurum, Turkey. E-mail: mkoc@atauni.edu.tr


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