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Japanese Journal of Clinical Oncology 32:262-265 (2002)
© 2002 Foundation for Promotion of Cancer Research

A Case of Recurrent Metastatic Thymoma Showing a Marked Response to Paclitaxel Monotherapy

Shigeki Umemura1, Yoshihiko Segawa1, Keiichi Fujiwara1, Ichiro Takata1, Nobuhiko Seki1, Yoshiyuki Tokuda1, Kenji Eguchi1 and Koichi Mandai2,+

Departments of 1 Internal Medicine and 2 Pathology, National Shikoku Cancer Center Hospital, Matsuyama, Japan

We describe a case of recurrent metastatic thymoma showing an excellent response to salvage paclitaxel monotherapy. The patient had undergone a series of platinum-based chemotherapy treatments during the previous 20-month period and the patient’s disease was considered resistant to such therapy at the start of treatment with paclitaxel. This is the first report to suggest that paclitaxel has anti-thymoma activity.

+ For reprints and all correspondence: Shigeki Umemura, Department of Internal Medicine, National Shikoku Cancer Center Hospital, 13 Horinouchi, Matsuyama, Ehime 790-0007, Japan. E-mail: sumemura@shikoku-cc.go.jp


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