Skip Navigation


Japanese Journal of Clinical Oncology Advance Access originally published online on November 12, 2007
Japanese Journal of Clinical Oncology 2007 37(11):874-877; doi:10.1093/jjco/hym108
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
37/11/874    most recent
hym108v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Takahashi, D.
Right arrow Articles by Okamura, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Takahashi, D.
Right arrow Articles by Okamura, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© 2007 Foundation for Promotion of Cancer Research

Primary Ewing's Sarcoma Family Tumors of the Lung – a Case Report and Review of the Literature

Daijiro Takahashi1, Jun Nagayama1, Yoshihisa Nagatoshi1,, Jiro Inagaki1, Kenichi Nishiyama2, Ryohei Yokoyama3, Yosio Moriyasu4, Kenji Okada4 and Jun Okamura5

1 Section of Pediatrics, National Kyushu Cancer Center
2 Department of Pathology
3 Department of Orthopaedics, National Kyushu Cancer Center
4 Department of Pediatrics, Fukuoka National Hospital
5 Institute for Clinical Research, National Kyushu Cancer Center, Minami-ku, Fukuoka, Japan

For reprints and all correspondence: Yoshihisa Nagatoshi, Section of Pediatrics, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan. E-mail: ynagatos{at}nk-cc.go.jp

Received March 25, 2007; accepted July 8, 2007

Ewing's sarcoma family tumors (ESFT) have been reported to originate in a variety of sites, most commonly in the extremities. We herein report a case of a primary ESFT of the lung presenting in an 8-year-old boy. A histological examination of hematoxylin–eosin stained sections showed a homogeneous population of closely packed small neoplastic cells. The tumor cells were strongly positive for CD99/MIC2 and negative for the leukocyte common antigen, myoglobin, desmin, epithelial membrane antigen, AE1/AE3 and synaptophysin. The patient was treated with neoadjuvant chemotherapy and surgery. Nine months later, he is in good condition and chest CT scans have revealed no evidence of either local recurrence or distant metastasis. Cases of ESFT of the lung have been reported in recent years but there are still few reports of primary ESFT of the lung. To date, only eight cases of ESFT of the lung have been reported in the literature. This is the first report of an ESFT of the lung occurring in a patient under 10 years of age. The clinical course and therapeutic management of ESFT are also discussed.

Key Words: Ewing's sarcoma • lung • MIC2


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.