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Japanese Journal of Clinical Oncology Advance Access originally published online on January 29, 2009
Japanese Journal of Clinical Oncology 2009 39(3):192-194; doi:10.1093/jjco/hyn154
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© The Author (2009). Published by Oxford University Press. All rights reserved

Acute Inflammation and Micrometastasis Proliferation: A Fissure in the Uniformitarian Façade of Cancer

Alberto Carmona-Bayonas

Haematology and Medical Oncology Department
Hospital Universitario Morales Meseguer
Calle Marqués de los Vélez sin número
30008 Murcia
Spain
E-mail: alberto.carmonabayonas@gmail.com

The first 10% of the full text of this article appears below.

To the Editor:

The principle ‘Natura non facit saltum’ attributed to Carl Linnaeus in the eighteenth-century had a deep influence in the current perception of natural processes, including some medical issues. In particular, geology, evolution and mass extinctions were once considered the tireless work of slow, gradual and continuous processes. That conception was called uniformitarianism and was defended by Lyell, the eminent nineteenth-century geologist. In contrast, George Cuvier believed that cataclysms and natural disasters disrupted the uniform rhythm of progressive evolution. Likewise, the predominant opinion implied that tumor progression did not make leaps, since cancerous cells proliferated and thrived without rapid skips and jumps. Gompertzian models are somehow a reminiscence of these . . . [Full Text of this Article]

Conflict of interest statement


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