Skip Navigation



Japanese Journal of Clinical Oncology Advance Access published online on August 12, 2006
Japanese Journal of Clinical Oncology, doi:10.1093/jjco/hyl079
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
36/10/649    most recent
hyl079v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Sasaki, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sasaki, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2006 Foundation for Promotion of Cancer Research
Received April 14, 2006
Accepted June 21, 2006

Original Article

Postoperative Radiotherapy for Patients with Prostate Cancer in Japan; Changing Trends in National Practice between 1996-98 and 1999-2001: Patterns of Care Study for Prostate Cancer

Tomonari Sasaki 1 *, Katsumasa Nakamura 2, Kazuhiko Ogawa 3, Hiroshi Onishi 4, Yuki Otani 5, Masahiko Koizumi 6, Yoshiyuki Shioyama 2, and Teruki Teshima 5, The Japanese Patterns of Care Study Working Subgroup of Prostate Cancer

1 Department of Radiology, National Kyushu Cancer Center, Fukuoka, Japan
2 Department of Clinical Radiology, Kyushu University, Fukuoka, Japan
3 Department of Radiology, University of the Ryukyus, Okinawa, Nakagami-gun, Japan
4 Department of Radiology, Yamanashi University, Chuo, Yamanashi, Japan
5 Department of Medical Physics and Engineering, Nakagami-gun, Osaka University, Osaka, Japan
6 Department of Radiological Technology, School of Health Sciences, Fujita Health University, Toyoakei, Aichi, Japan

* To whom correspondence should be addressed.
Tomonari Sasaki, E-mail: tsasaki{at}nk-cc.go.jp


  Abstract

Objective: To evaluate the changing trends of standards and practices for postoperative radiotherapy (RT) for patients with prostate cancer in Japan.

Methods: The Japanese Patterns of Care Study (PCS) conducted a national survey in 84 institutions from 1996 to1998 (PCS96-98) and 76 institutions from 1999 to 2001 (PCS99-01). Detailed information relevant to RT was collected on a total of 169 patients (64 from 1996 to1998 and 105 from 1999 to 2001) with prostate cancer who had undergone radical prostatectomy.

Results: The fraction of clinical T3-4 tumours before prostatectomy decreased from 63% in the period 1996-98 to 26% in the period 1999-2001 (P = 0.0004). The pre-RT prostate-specific antigen level was significantly lower in 1999-2001 than in 1996-98 (P = 0.0002). We did not find a significant difference in the percentage of patients who received pelvic irradiation in the time periods between PCS96-98 and PCS99-01 (P = 0.18). Although the median radiation doses of 60 Gy were not changed between the surveys, various doses (from 20 to 74.6 Gy) were delivered to the prostatic bed. In the 1999-2001 survey, 73 of 105 patients received a median dose of 56 Gy in an adjuvant setting, while the other 32 received a median dose of 60 Gy in a salvage setting (P = 0.0015).

Conclusion: These data suggest that consensus has not been reached on the practice and management of postoperative RT for patients with prostate cancer in Japan.

Keywords: postoperative radiotherapy; prostate cancer; Patterns of Care Study.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.