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Japanese Journal of Clinical Oncology Advance Access published online on January 25, 2007

Japanese Journal of Clinical Oncology, doi:10.1093/jjco/hyl129
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© 2007 Foundation for Promotion of Cancer Research

Initial Experience with the Quality Assurance Program of Radiation Therapy on behalf of Japan Radiation Oncology Group (JAROG)

Koichi Isobe1,, Yoshikazu Kagami2, Keiko Higuchi3, Takeshi Kodaira4, Masatoshi Hasegawa5, Naoto Shikama6, Masanori Nakazawa7, Ichiro Fukuda8, Keiji Nihei9, Kana Ito10, Teruki Teshima11 and Masahiko Oguchi12

1 Department of Radiology, Chiba University Hospital, Chiba
2 Radiation Oncology Division, National Cancer Center Hospital, Tokyo
3 Department of Radiology, Gunma Prefecture Cancer Center, Ohta, Gunma
4 Department of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya
5 Department of Radiation Oncology, Nara Medical University, Kashihara, Nara
6 Department of Radiology, Shinshu University School of Medicine, Matsumoto, Nagano
7 Department of Radiology, Jichi Medical University, Shimotsuke, Tochigi
8 Department of Radiology, Jikei University School of Medicine, Tokyo
9 Radiation Oncology Division, National Cancer Center Hospital East, Chiba
10 Department of Radiology, Juntendo University School of Medicine, Tokyo
11 Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka
12 Department of Radiation Oncology, Cancer Institute Hospital, Tokyo, Japan

For reprints and all correspondence: Koichi Isobe, Department of Radiology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan. E-mail: isobeko{at}ho.chiba-u.ac.jp

Received September 18, 2006; accepted October 4, 2006

BACKGROUND: We evaluated the efficacy of our quality assurance (QA) program of radiation therapy (RT) in a prospective phase II study. This is the first description of the experience of the Japan Radiation Oncology Group (JAROG) with this program.

METHODS: Clinical records, all diagnostic radiological films or color photos that depicted the extent of disease of 37 patients with stage IEA extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) were collected for review. Radiation therapy charts, simulation films or digitally reconstructed radiographs, portal films and isodose distributions at the central axis plan were also reviewed. All documents were digitally processed, mounted on Microsoft PowerPoint, and for security returned from researchers by mail in CD-ROM format. The QA committee members reviewed all documents centrally, utilizing the slide show functionality.

RESULTS: All patients were prescribed their specified dose to the dose specification point in accordance with the protocol. Three patients were regarded as deviations, because of a smaller margin than that specified in the protocol (n = 2) or a prolonged overall treatment time (n = 1). No violations were observed in this study.

CONCLUSIONS: This is the first report with regard to the QA program in MALT lymphoma. We demonstrated that our QA program was simple and inexpensive. We also confirmed that the radiation oncologists in Japan adhered closely to the protocol guidelines.

Key Words: MALT lymphoma • quality assurance • QA program • radiation therapy


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T. Toita, M. Oguchi, T. Ohno, S. Kato, Y. Niibe, T. Kodaira, T. Kazumoto, M. Kataoka, N. Shikama, M. Kenjo, et al.
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