Skip Navigation



Japanese Journal of Clinical Oncology Advance Access published online on August 9, 2008
Japanese Journal of Clinical Oncology, doi:10.1093/jjco/hyn072
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrowOA All Versions of this Article:
38/8/534    most recent
hyn072v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Toyoda, Y.
Right arrow Articles by Tsukuma, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Toyoda, Y.
Right arrow Articles by Tsukuma, H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Trends in Lung Cancer Incidence by Histological Type in Osaka, Japan

Yasuhiro Toyoda1,2, Tomio Nakayama1, Akiko Ioka1 and Hideaki Tsukuma1

1 Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Disease
2 Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan

For reprints and all correspondence: Tomio Nakayama, Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Disease, 537-8511 3-3 Nakamichi 1-chome, Higashinari-ku, Osaka 537-8511, Japan. E-mail: nakayama-to{at}mc.pref.osaka.jp

Received March 11, 2008; accepted July 13, 2008

Background: In Japan, an increase in age-adjusted incidence rates of lung adenocarcinoma (ADC) and a decrease in lung squamous cell carcinoma (SQCC) have been reported.

Methods: The number of lung cancer incidence, age-adjusted rates, and age-specific rates by birth-cohort according to histological type were examined using the data from Osaka Cancer Registry.

Results: The numbers of lung cancer incidence among men and women have increased, particularly in ADC. The age-adjusted incidence rates of ADC among men and women have continuously increased, while those of SQCC and small cell carcinoma (SMCC) turned to decrease since 1990s. A trough of lung cancer incidence rates was observed among men in 1935–39 birth-cohorts. The declining trend appeared in 1955–59 birth-cohorts. Lung cancer incidence rates among women have increased since 1895–99 birth-cohorts, but those rates leveled off or decreased in 1950s birth-cohorts. Trends of ADC by birth-cohort were almost the same as those of all histological types. The SQCC among men peaked in 1915–19 birth-cohorts, and decreased in the subsequent birth-cohorts. The SMCC among men peaked in 1920s birth-cohorts, and decreased or leveled off in the subsequent birth-cohorts.

Conclusions: Lung cancer incidence rates by birth-cohorts were almost parallel to the smoking prevalence. However, those for ADC among young women in 1950s birth-cohorts were not parallel to the smoking prevalence, which requires careful monitoring to confirm such findings.

Key Words: lung cancer • incidence • histological type • birth-cohort


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.